One of the key ways The Joint Commission establishes standards for sustaining The National Patient Safety Goals are used to ensure patient safety throughout all healthcare settings (NPSGs). The Joint Commission reviews the NPSGs on a regular basis to verify that healthcare organizations are focusing on avoiding significant causes of patient harm. Surgical infection prevention, prescription mistakes, inpatient suicide, and particular clinical difficulties like as falls and persistent wounds are also areas of study’s. Along with accessibility, acceptability, efficacy, efficiency, and people centeredness, one of the features of high-quality treatment is patient safety. It includes a variety of factors that are critical to providing high-quality health care. It's about safe surgical treatment and delivery, as well as safe injections, blood, pharmaceutical, medical device, and organ, tissue, and cell transit and donation. It also covers biomedical waste management, infection control in hospital settings, and much more. Objective to determine how well staff nurses understand patient safety objectives. And to determine whether there is a link between education level and certain demographic characteristics. Methodology: A non-experimental Descriptive design carried out among 100 staff nurses. Non-probability purposive sampling technique was used and was statically analyzed after collecting the data through structured questionnaire was prepared for data collection. Ethical clearance was taken from the Institutional ethics committee. Data analysis was done using descriptive statistics. Results The goal of this study was to determine how much information people had of staff nurses in a chosen hospital in Pune about patient safety objectives. The major findings are 67 (67%) of staff nurse having average knowledge, the remaining 33 (33%) had good knowledge and 0(0%) had poor knowledge. There was no statistically significant relationship between staff nurse understanding of safety objectives and selected socio demographic characteristics.