Background: clinical pathway is a multidisciplinary outline of anticipated care, placed in an appropriate time frame, to help a patient with a specific condition move progressively through a clinical experience to positive outcomes’. It designed to streamline patient care delivery, maximize efficiency, minimize cost, improve communication between doctors and nurses, increase patient satisfaction with the service and improve the care outcome. They address variability in practice by having providers agree prospectively on a common regimen of clinical intervention. Method: in this article, we review a state of art of over view about application of clinical pathway in health care. Results: this review confirmed a great impact of clinical pathway application on patient's outcomes as level of pain, anxiety, satisfaction, post-operative complications, length of stay in hospital and quality of care given by the health team. Conclusion: application of clinical pathway enhance the quality of health care services