Objective: Phyllanthus emblica is an ethnomedicinal plant that has several medicinal claims and it hasn't been explored thoroughly. Various parts of the plant are used medicinally such as antioxidant, anti-inflammatory, analgesic and anti-pyretic etc. The study aims to explore the different qualitative, quantitative, and antifungal aspects of Phyllanthus emblica. Materials and methods: The present study was conducted to evaluate the anti-microbial activity of Phyllanthus emblica extracts against Grampositive bacteria (Staphylococcus aureus), Gram-negative bacteria (E. coli), and Fungal (Candida albicans). The agar well diffusion method was used to test the antimicrobial activity. Result & Discussion: Phyllanthus emblica extracts exhibited potent antibacterial and antifungal against all the selected bacterial and fungal species. The extracts exhibited the growth inhibitory activity in a dose-dependent manner. Also, the study reveals Phyllanthus emblica shows good antimicrobial activity. Conclusion: The Phyllanthus emblica plant extracts could be used as an antimicrobial after comprehensive in-vitro biological studies.