Abstract: Objective: to study the risk factors, clinical and pathogenetic features for the subtypes of ischemic stroke at a young age in a comparative aspect. During 2017-2019, 74 patients with ischemic stroke (IS) or transient ischemic attack (TIA) were under observation, 48 men and 26 women. All patients were divided into 2 groups: I-st (main) group included 33 patients aged 20 - 44 years (aged of 40.5 ± 3.1 years); II-nd (comparative) group - 41 patients age group over 60 years (aged of 67,9±3,9 years). According to the TOAST criteria, a stroke of an unknown etiology occurred in young people (49%), in old-aged - cardioembolic (39%) and atherothrombotic subtypes (31%). Among the risk factors for ischemic stroke in young people revealed a combination of bad habits, and in the old-aged category, such modulated factors as arterial hypertension, 2nd type of diabetes mellitus, hypercholesterolemia are revealed. These findings confirm the urgency of the problem of cerebral infarction of a young age and the need for further implementation of the latest examination methods and a deeper study of the cardiovascular system.