ABSTRACT This paper presents the relevant aspects of marketing research on soft and transdermal drugs on the market of the Republic of Uzbekistan. A structured content analysis of soft and transdermal drugs was carried out by comparing quantitative and qualitative characteristics according to the criteria: dosage form, pharmacotherapeutic group, origin, far-abroad countries, CIS countries, domestic. Revealed a relatively greater number of registered drug forms ointments, suppositories. It is shown that antifungal agents of domestic producers 7.8%, CIS countries –9.4%, foreign manufacturers 9.8% prevail on the market; antiseptic - domestic - 16.3%, CIS - 7.6%, foreign - 3.2%; anti-inflammatory domestic production is 19.2%, CIS-11.17%, foreign 32.8%. A not small list of pharmacotherapeutic groups of ointments is known due to poor absorption, old technologies lose their relevance. Gels have replaced, and what is relevant for the development and introduction into domestic production of new or well-known drugs in the form of gels. In the territory of the republic, gels are mainly registered and used abroad (36%), when domestic manufacturers produce only 5% of the soft drugs produced. Gels are of particular interest because of their structural, mechanical, and physical properties. It should also be noted that some pharmaceutical groups, such as immunosuppressants, drugs for the treatment of eryctile dysfunction, hepatoprotectors, androgens and its synthetic analogues, drugs that promote normal scarring, corticosteroids account for a small% and are registered only by foreign manufacturers, and then in a small amount i.e. not registered in the CIS countries and domestic manufacturers. The results indicate the feasibility of further research to assess the prospects of creating and introducing new topical drugs, in the form of soft drugs (gels, suppositories), new and a combination of those already produced by domestic manufacturers.