Background: Among women, incidence rates for breast cancer significantly exceeded those for other cancers in both transitioned and transitioning countries, it remaining as a remaining as most commonly diagnosed cancer and the prominent cause of cancer death in women worldwide. The present study was conducted to assess Clinico-radiopathological Features and Biological Behavior of Breast Cancer in Young Indian Women. Materials and Methods: A prospective descriptive study was done among women aged less than 40 years diagnosed with breast cancer. In patients with suspicious clinical or ultrasound findings or if biopsy yielded malignancy, digital mammography was performed. All the BI-RADS 4 and 5 lesions and few of the BI-RADS 3 lesions were biopsied, and samples were sent for histopathology (HPE) and immunohistochemistry (IHC) examinations. The data was collected on Microsoft Office Excel 2013 and statistical analysis was performed using IBM SPSS version 21(Illinois, Chicago). P value <0.05 was considered significant.