Rhino cerebral Mucormycosis and aspergillosis are uncommon but lethal diseases in people with immunocompromised persons. These infections typically spread through inhalation , but they can also enter through ingestion and trauma. Here, presenting a case of mucormycosis and aspergillosis in a 24-year-old immunocompetent male patient with no known comorbidities who presented initially with complaints of headache and on subsequent investigations revealed both mucormycosis and aspergillosis involving the paranasal sinuses, nose, and cerebrum. The patient was treated with amphotericin B and Posaconazole.