Online ISSN: 2515-8260

An Observational Study on Clinico-etiological Profile and Outcomes of Children with Status Epilepticus

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Nand Kishor Singh1 , Shailendra Kumar2 , Rakesh Kumar3 , Prem Kumar4

Abstract

Objectives: We conducted this research to characterise the clinical-etiological profile of children with status epilepticus (SE) who are younger than 12 years old, as well as to investigate the risk factors and underlying causes of RSE, the course of the condition at the end of the hospital stay, and indicators of a good or bad outcome in SE. Materials and Methods: This hospital-based prospective observational study is conducted from April 2022 to January 2023 in a paediatric intensive care unit of a tertiary care referral hospital in Bihar, India. The study included 111 youngers than 12-year-olds who were admitted in a row with SE. The principal investigator gathered and entered the data regarding the parameters in a standardised proforma after thorough review and necessary inquiries. The final result was documented after the patient's hospital stay. The acquired data were evaluated to find important variables that might predict the result and the risk factors for RSE. Results: After infancy, the age period of 1-6 years was reported to have the highest prevalence of SE. Boys made up 51.4% of cases while girls made up 48.6%. Meningoencephalitis and febrile status were the two most frequent causes of status. Anaemia was revealed to be a risk factor (odds ratio=8.68) and to be strongly linked with RSE (pvalue =0.001). 9 (8.1%) of the kids died. Significantly, an adverse outcome was seen more frequently in children who remained pain responsive or unresponsive 6 hours following seizure control (p value 0.01). The advancement of RSE and worse result were substantially linked with delaying the administration of the first anti-epileptic drug (AED). Conclusion: We discovered that RSE was substantially linked with anaemia and a delay in the use of the first AED. Additionally, there was a strong correlation between poor outcomes and kids who were still in pain or unresponsive 6 hours following seizure control.

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