Abstract. Genome, material of genetic, within all living species consisting of DNA (or) RNA in mRNA. Genome analysis is the process of identifying, measuring or comparing the features of genome lists sequencing DNA, Structural variation, expression of gene, regulatory element annotation and genomic scale of functional element annotation. Genome sequencing is the process of storing the data plays the major role in different field of engineering. It also matters in genome sequence analysis for storing the raw samples, sequenced genome and repetitive data. This paper gives the overview of genome sequencing, its types and storing concepts.