Aims and Objectives: The objective of this review is to search the literature on repositioners and present as to how it has emerged as a crucial treatment plan in modern orthodontics. The conventional orthodontic treatments were deemed tiresome since a lot of impressions had to be taken which demanded more clinical hours and efforts in the laboratories to manufacture appliances. Apart from this, aesthetics, and patient discomfort such as pain, longer duration of treatment, continuous wire adjustments, restrictive dietary habits, poor oral hygiene, patient compliance, were other areas of concern since a long time now. Clear aligners, which is a concatenation of removable thermoplastic polyurethane aligners, came into limelight as an aesthetic, comfortable, alternative to the traditional orthodontic treatments. This system makes use of CAD/CAM technology which plays a pivotal role in the success of clear aligners. This literature review aims to discuss about the advancements in the clear aligner system over the years and how it has proved to be an indispensable asset in Dentistry. However, certain limitations still need to be addressed to improve the efficiency of this system.