Hypertension is a global problem, and its incidence and prevalence increase with the declining glomerular filtration rate (GFR) in Chronic kidney disease. It is also the single most powerful predictor of cardiovascular (CV) disease and mortality. ABPM allows a serial BP measurements at specified time intervals throughout a 24-hour period, thereby providing a better assessment of the normal fluctuations in BP levels associated with a person’s daily activities and sleep. Hence, ABPM is particularly useful in evaluating the patient with highly variable BP with wide discrepancies between the BP readings obtained in and outside office. The association between masked hypertension and lower eGFR was observed only in those participants with elevated night-time BP. In this study, we aimed to determine the effect of circadian rhythm over hypertension in CKD and non-CKD patients and the associated prognostic value by assessing the target organ damage