Abstract Drugs such as adreno-corticosteroids, corticosteroids, purine analogues, antibiotics, immunomodulators, and 5-aminosalicylic acid have become the foundations in management therapy for Ulcerative Colitis (UC). These medicaments remain available in the variety of forms are used an orally and topically to reduce inflammation of the colon and rectum. There can be seen the imbalance of intestinal beneficially acting bacteria triggered an inapt, intense, and enduring mucosal immune retort that leads to the intestinal tissue impairment in an individual. Nonetheless, all these drugs are useful for treatment tolerated with some shortcomings side-effects. From the beginning to the end of human life, natural plants or plant products play an important part. In this existing review, the authors summarize the revisions relating to the natural products practiced by UC patients as a substitute management process for each induction or upkeep management.