Abstract:LYMPHADENOPATHY (LAP) or ADENOPATHY is a any disease of the lymphnodes which is abnormal in size, number and consistency. Lymphadenopathy is a most common condition in any form of disease which is noticed by a physician .But it is not a peculiar symptom of any disease. An inflammatory type of lymphadenopathy is called as LYMPHADINITIS. In this review Article we can see the classification of lymphadenopathy pathogens, clinical approach and clinical evaluation of lymphadenopathy and differential diagnosis. Depending upon the size and extent of lymphadenopathy we can evaluate the condition of the patient and give appropriate treatment.