BACKGROUND: - Stressors have a major influence upon mood, our sense of well-being, behavior, and health. Acute stress responses in young, healthy individuals may be adaptive and typically do not impose a health burden. OBJECTIVES -To assess the level of stress among caregivers of individuals with mental disorders attending psychiatric OPD of selected hospitals in the city .To associate the level of stress among caregivers of individuals with mental disorders with selected demographic variables.METHODS - A descriptive research design was used to accomplish the objectives. Sample size: - 100 caregivers for the toolA pilot study was conducted on 10 samples to refine the methodology and find the feasibility of the study.100 caregivers of individualswith mental disorders who fulfilling the inclusion criteria were selected for the main studyRESULT- According to the results,75% of caregivers have moderate level of stress and 25% had severe level of stress. Andhighest stress score were in the area of role performance with modified mean i.e. 2.15 so, caregivers may perceive challenges regarding the caring of individuals with mental disorders.