Introduction: Wilson’s disease is inherited in autosomal recessive pattern and can manifest in the form of hepatic, neurological or psychiatric symptoms. The neurological manifestations are still a clinical enigma and are being studied continuously for a better understanding. Aims: To describe the range of abnormalities in brain magnetic resonance imaging (MRI) of patients with Wilson’s disease having neurological manifestations and their correlation with clinical findings and to evaluate the sensitivity of different MRI brain sequences in identifying the lesions in these patients Materials and Methods: A descriptive cross-sectional study was conducted in the department of radiology, Nil Ratan Sircar Medical College and Hospital for a duration of one year from August 2021 to July 2022. A total of 23 patients of Wilson’s disease having neurological manifestations who attended the medicine or neuro-medicine outpatient department of Nil Ratan Sircar Medical College and Hospital, Kolkata were included in the study.