Blood groups plays a vital role in the field of medicine. There is a clear association between ABO blood group types, Secretor status and von Willebrand factor. Deficiency of vWF leads to Hemorrhagic disorders, while elevated levels are a risk factor for thrombosis. Earlier studies state that the O group individuals have prolonged bleeding time and clotting time. Very few studies were done correlating the variations of bleeding time and clotting time and secretor status and von Willebrand factor. The objective of this study was to assess the relationship between Bleeding time and clotting time among various ABO Blood group types and secretor status and also to identify any gender difference among the different ABO blood group types. This is a cross sectional study including 150 Undergraduate students of age group 17 to 20 years. Bleeding time (by Duke’s filter paper method) ,Clotting time (by Wright’s capillary tube method) and secretor status (by weiner Indirect Haemagglutination test) was determined after obtaining an informed consent from the students. In our study, bleeding time was prolonged among O group secretor and have thinnest blood and are at risk for bleeding tendencies like epistaxis and clotting time less than 4 minutes is more in B group secretors and are at risk for thrombotic diseases like coronary artery disease and atherothrombotic diseases. Gender wise bleeding time and clotting time were higher in females than in males.