AbstractBackground- The State Transportation Sector manpower, mainly bus drivers and conductors are subjected to the consequences of acquiring musculoskeletal defects in addition to other morbidities like ocular, gastric, and psychological diseases. They undergo incompatible and unpredictable working scenarios, pressure of maintaining daily schedules, bad eating habits, and lack of proper sleep and rest due to multi-variable shifts. The resultant morbidities noticed may compromise their health, thus affecting the overall professional outcome. Objectives- The current study is laid out with a motive for the assessment of health status of bus drivers and conductors providing their services at a Bus Depot from Central India. It is more focused on identifying the factors that have a major effect on their performance and health, which would ultimately pave way for appropriate measures to be undertaken to benefit these workers, so that they can lead a mentally, socially and economically productive life. Methodology- This Cross- Sectional Study is going to be held at Wardha City Bus Depot, Maharashtra. A total of 304 participants, out of which 152 bus drivers and conductors each are meant to be enrolled for the same. A questionnaire comprising of Sociodemographic details and Occupational-related morbidities will be distributed amongst the candidates for data accumulation. The assimilated information will be analyzed via means of SPSS Software including calculation of Descriptive Statistics, frequencies and percentages. Expected Result- The analysis of data and appropriate statistical tests will contemplate its results. Conclusion- The conclusion will be drawn after completion of the proposed study.