Introduction: Due to its protracted duration, toxicity, high expense, and unfavourable results, the treatment of multidrug-resistant (MDR)/extensively drug-resistant (XDR) tuberculosis (TB) has proven difficult during the past few decades. Methods: A prospective study with 50 drug-resistant tuberculosis patients who are taking bedaquiline as part of a treatment regimen and who meet the requirements of being over 18 years old, all genders, and having biological samples that show drug resistance that has been confirmed by phenotypic or genetic testing. Results: Nausea was the most frequent side effect, followed by diarrhoea, joint discomfort, anorexia, and itching. There was no hepatotoxic effect. Conclusion: A regimen using bedaquiline produced positive results. The benefit clearly justifies the risk even though bedaquiline and concurrent anti-TB medicines have the potential to lengthen QTc interval