Background: In the intensive care units, acute kidney injury (AKI) has been recognized as a distinct risk factor for mortality. The goal of this retrospective study was to identify the risk factors for death in AKI patients as well as the impact of AKI on in-hospital mortality in a general medical ward of a tertiary care hospital. Methods: A detailed patient's history was obtained, and routine blood tests, such as blood urea, serum creatinine, urine routine, abdominal ultrasound, serology for leptospirosis, enteric fever, peripheral smear for the malarial parasite, and other pertinent investigations, were carried out. Once a diagnosis was made, the therapy was started with the patients' etiological factors adjusted when it was possible