Aim: A clinico pathological evaluation of soft tissue tumors in tertiary care centre of North bihar Methods: This retrospective study was carried out in the Department of Pathology, Darbhanga Medical College, Laheriasarai, Darbhanga, Bihar, India, from January 2020 to January 2021. Total 100 patients of all the soft tissue tumors, both benign and malignant were included in this study. Results: Total 100 cases of soft tissue tumours were included in this study. It has slightly male preponderance with a male to female ratio was 1.38:1. Benign soft tissue tumours formed 84% of all soft tissue tumours while malignant soft tissue tumours constituted 16%. The commonest benign tumour was Adipocytic (52%) of all tumours of soft tissue followed by vascular tumours (20%), peripheral nerve sheath tumours (17%), fibrous tumours (2%), fibrohistiocytic tumours (2%) smooth muscle tumours (2%) and tumours of uncertain differentiation (1%). The benign adipocytic tumours accounted for the majority of benign soft tissue tumours (47%) followed by vascular tumours (17%) &Benign peripheral Nerve Sheath Tumors (16%),Benign Fibrous Tumor (2%),Benign Fibrohistiocytic Tumors (1%), Benign tumours of smooth muscle (1%) and tumours of uncertain differentiation are nil encountered. 30% benign soft tissue tumours were seen in extremities followed by head and neck 27% and for the malignant soft tissue tumours mainly lower extremities (6%) followed by Head & Neck (5%). Conclusion: The clinicopathological evaluation is still the gold standard for the proper diagnosis of soft tissue tumors