Background: Accurate open reduction and internal fixation of metacarpal fractures are required in unstable fractures where closed treatment technique yield poor functional outcome which usually is less than 5% of hand fractures. Mini plates and screws when used in properly selected cases provide rigid fixation allowing early mobilization of joints and hence good functional outcome. Patients and methods: In 25 patients with closed metacarpal shaft fractures treated with mini plates and screws between December 2017 to December 2019 at Vijayanagara institute of medical sciences Ballari. The functional outcome was assessed using Disability of Arm, Shoulder and Hand (DASH) score and Visual Analog Score (VAS) over a period of two years in prospective manner. Results: In our study of metacarpal shaft fractures treated with plate osteosynthesis all the cases showed bone union (100%). The functional result is Excellent in 84% of the patients (21 of 25 cases), good in 12% of cases (3of 25 Cases), poor in 4% of cases (1 of 25 cases). 2 patients developed superficial wound infection which settled with daily dressing and antibiotics and this does not affect the final outcome. Conclusions: Plate and screw fixation is a good option for treating closed metacarpal shaft fractures, where other modalities of fixation are less effective, the rigid stable fixation provided by plating withstands load without failure allowed early mobilization and achieved good functional results.