Abstract Aim: The aim of the present study to evaluate the acute biliary pancreatitis. Methods: This was a prospective observational study conducted in the Department of General Surgery, , Anugrah Narayan Magadh Medical College & Hospital, Gaya Bihar, India for 1 year. Total 120 patients with biliary pancreatitis, fulfilling the diagnostic criteria and giving consent to be included in this study. Laboratory investigations including a complete blood count, serum amylase or lipase, renal profile, lipid profile, liver function test and serum electrolytes were done and data recorded. Further radiological evaluation was done with contrast enhanced CT and/or magnetic resonance cholangiopancreatography (MRCP). Results: The mean age of patients with biliary pancreatitis was 52.75 years. Majority of them belonged to age group of 50-60 years. The most common signs and symptoms were pain abdomen (97.5%) and abdominal tenderness (97.5%) followed by nausea (64.17%), vomiting (57.5%), fever (25%), jaundice (45.83%), Pain radiating back(10.83%), Tachycardia (5.83%). Serum amylase and lipase elevation was diagnostic for pancreatitis and was noted in all the cases. Haematocrit values were raised (>44%) in 30% cases with mean±SD value of 41.97±6.87. Creatinine values were increased (>1.5 mg%) 33 % cases with mean±SD value of 1.42±1.13. Modified CT severity index was applied to all cases which categorised them into mild 21%, moderate 67% and severe category 12%. 46.67% cases were diagnosed with pleural effusion, 44.17% cases had ascites, 22.5% had hepatomegaly and 22.5% were diagnosed to have splenomegaly. Conclusion: Relevant clinical history, ultrasonography and computed tomography scan of pancreas are helpful in diagnosis of pancreatitis. The computed tomography scan was a better imaging modality as compared to ultrasonography.