Influenza virus is an acute respiratory disease caused by the influenza A or influenza B virus. These virus show effect mainly during winter season it often occurs in outbreaks and epidemics worldwide. Influenza virus is respiratory viral disease. Significant numbers of influenza virus particles are present in the respiratory secretion of infected persons , so infection can be transmitted through sneezing and coughing via large particle of droplets. The duration of influenza virus shedding in immune competent adult patients is around 5 to 10 day or more and it can be show particularly in children, elderly adults, patient with chronic illnesses, and immune compromised hosts. If any person infected with influenza they show many symptoms such as high-grade fever, mayalgia, headache, and malaise. Some symptoms are found such as nonproductive cough, sore throat and nasal discharge. After that influenza can attack other organs like that the lungs, brain, heart but mainly it affect respiratory tract and patient can be admitted in hospital. We can prevent the influenza by using proper annual vaccination. If sever patient- we can early treatment by antiviral drugs. So, due to disease burden, we reviewed the currently finding in diagnosis and treatment of influenza.