Aim and objective:The aim of the study was to evaluate of Parenchymal Thyroid Diseases with multi-parametric Ultrasonography. Material andMethods: This study was conducted in the Department of Radiology at Maharishi markandeshwar institute of medical sciences and research Mullana, India, for the period of 1 year. Patientsweredivided into five groups such as group I (normal); group II had first detected, early untreated Hashimoto disease(EH);groupIII comprised of chronic Hashimoto patients that are under treatment and/or follow up (H); group IV had multinodular parenchymal hyperplasia (M); and group V had nodular hyperplasia with Hashimoto (HM). They underwent spectral Doppler ultrasound and acousticradiationforce impulse. Quantitative spectral doppler parameterssuch as resistivity index (RI), acceleration time (AT) and quantitative elastography such as shear wave velocity (SWV) was recorded.