Introduction: In India, oral cancer is one of the leading cancer today. Its incidence is 12.6 per 1,00,000 population. The premalignant lesion is a disease or syndrome if left untreated have significantly increased risk to develop cancer. Aim and Objective of the study: The objective of this study is to evaluate clinicopathological spectrum of oral cavity lesions at our tertiary care hospital. Materials and Methods: A detailed history-taking including age, sex, complaints and duration of symptoms, site, side etc. and with thorough clinical examination relevant investigations for consistency, diagnosis, benign or malignant was done and appropriate management has been done for these patients