Online ISSN: 2515-8260

A CROSS SECTIONAL ANALYTICAL STUDY TO EVALUATE THE PREVALENCE AND EARLY DIAGNOSIS OF NAFLD IN VARIOUS COMORBIDITIES USING LIPID PROFILE AND HEPATIC ENZYMES AS BIOMARKERS

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Chiluka Kiran1 , Sanath Kumar2 , Bandi Suman

Abstract

Background: Nonalcoholic fatty liver disease (NAFLD) is a global epidemic that is often asymptomatic and silent, and progresses slowly and is one of the most common causes of chronic liver disease. NAFLD affects a third of the world population with very much high prevalence among patients with diabetes mellitus, obesity, hypertension, dyslipidemia, hypothyroidism etc. The natural history of NAFLD ranges from pure steatosis to steatohepatitis (NASH) to cirrhosis and in some patientsto hepatocellular carcinoma (HCC). NAFLD has been found to be the hepatic components of metabolic syndrome which is one of the leading causes of chronic liver disease. This study aimed to determine the biochemical hepatic markers and lipid profile among NAFLD patients and their possible relationship with degrees of fatty liver and other comorbidities to aid the clinician tointervene early in order to delay the occurrence of complications associated with NAFLD.

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