Low back pain is the most common problem among chronic pain disorders in middle aged population. Epidural Steroid Injection (ESI) is one of the most commonly performed nonsurgical interventions 1 . Objective of study is to compare the efficacy of epidural steroid injection with & without Bupivacaine for low backache patients. Materials and Method: Two groups of 12 selected patients with chronic low backache were randomized for midline Inter laminar Epidural injection with 80 mg Methylprednisolone acetate with saline and Methylprednisolone acetate 80mg with 0.25% Bupivacaine. All patients received 3 injections at intervals of 2 weeks. They were assessed for degree and duration of analgesia (VAS) and any adverse effects. Results: Onset of pain relief was less in adjuvant group when compared to non-adjuvant group after ESI. VAS at the end of 6 weeks in both groups was almost same in both groups. There were no significant adverse effects. Conclusion: Epidural Steroid Injections significantly reduce radicular pain more with Bupivacaine