: Pain is almost a constant feature after hemorrhoidectomy and is the commonest reason for delayed patient discharge [1]. 0.2% Glyceryl Trinitrate (GTN) ointment has been used to treat anal fissure and pain relief in haemorrhoids, but the value of its use posthaemorrhoidectomy as an analgesic and in wound healing is unclear. The side effect of headache has often been an associated problem. Therefore, we designed this study to evaluate the analgesic effects of local application of 0.2% GTN for pain management after hemorrhoidectomy, and its role in would healing and the unwanted incidence of headache