Background: Obesity is a major public health problem in Indian healthy adults in urban and rural area. Cardio metabolic risk factors are frequently observed among those who have generalized obesity measured by Body Mass Index (BMI). However, there is limited study available on these risk factors in abdominal obesity in which normal BMI with central distribution of body fat, a phenotypically frequently observed healthy adults. So we conducted “A comparative study of cardio metabolic risk factors in generalized obesity, abdominal obesity and non-obesity in Indian healthy adults”. Materials and methods: A Cross sectional study was conducted among healthy adults in age group 20 to 45 years of both sex and 600 subjects were selected from general public, hospital staff and patient attendants, out of which 200 were non obese, 200 abdominal obese and 200 generalized obese. Study was conducted from November 2021 to June 2022. Abdominal obesity was defined as waist circumference >90 cm in males and >80 cm in females with or without generalized obesity and generalized obesity was defined as BMI >25 kg/m2 with or without abdominal obesity. Clinical and biochemical characteristics were collected using standard questionnaires and protocol. Data were analyzed using SPSS version 16.0. ANOVA test was applied for statistical significance. P value <0.05 was taken statistically significant.