Breast cancer affects women more than men. From puberty to death, breasts go through constant physical and physiological changes related to menstruation, pregnancy, and menopause. The goal was to classify different types of breast lesions and conduct a clinicopathological study on them.Methodology: In the present study carried out at the department of Pathology of ACSR Govt Medical College, Nellore AP during the period from January 2019 to June 2021 (18 months) a total number of 150 FNAs were performed on patients with breast lumps. Results: The youngest patient in this study was 12 years and the oldest 79 years. Majority of the patients were in the age group of 21-40 years. In majority of the patients i.e. From 150 aspirates, 65 were from the right breast and 70 from the left. 15 cases involved both breasts.Upper outer quadrant of right and left breast had 39 and 35 cases of breast lumps, respectively. Lower outer quadrant of the right breast had 11 cases and upper medial had 11 cases. Two breast cases showed diffuse all-quadrant involvement. 2 of the 45 cases were clinically suspected of malignancy and 1 of fibroadenosis, but FNAC showed fibroadenoma. Three clinicocytologically discordant cases lacked excision biopsy. 15 cases of breast cancer were in the right breast and 9 in the left. Upper outer quadrant is most common for breast lumps. Side and quadrant distribution are shown below. All 20 cases were confirmed by excision biopsy. FNAC diagnosed 18 IDC NOS cases and 2 IDC Mucinous cases.CONCLUSION: FNAC is the procedure that is most commonly used since it is an initial outpatient procedure that is straightforward, risk-free, quick, and dependable. Additionally, it contributes to an early preoperative diagnosis of any lump in the breast.