One of the difficulties diabetic women face is recurrent yeast infection of the vulva and vagina.The substantial increase in the incidence of vulvovaginal candidiasis especially in diabetic women demands prompt treatment that would restore the normal vaginal flora and also keep the blood sugar levels in check. Homoeopathy, a safe alternative method, based on the idea of individualization uses a holistic approach towards these cases. Being a safe and cost-friendly intervention, it not only relieves the complaints of the individuals but also help them boost up their selfesteem. This study aims at exploring the effectiveness of Homoeopathic medicines in vulvovaginal candidiasis in women with type II Diabetes mellitus. In this study, 15 women with Candidiasis and type II Diabetes mellitus selected from SKHMCH OPD and IPD and rural centers, were prescribed with the homoeopathic similimum after thorough case taking and analyzing the investigation reports. Follow ups were taken every month for three months and the improvement of the cases were assessed based on the signs, symptoms and investigation reports. After the administration of the Homoeopathic similimum, notable improvement was elicited in the signs and symptoms and also the lab reports. Mercurius solubilis was noted to be the most effectively used medicine and 200 th potency was noticed as the most frequently used potency.