Background: Varicella-zoster virus (VZV) is known for causing two highly infectious diseases-Varicella (chickenpox) and Herpes Zoster (shingles). The reactivation of the varicellazoster virus causes Herpes zoster, also called as shingles. In the contrast, Herpes zoster usually arises in adults or the elderly. This virus reactivates mainly due to failure of the immune defense system to control the latent replication of the virus.