Background: Cholelithiasis is a chronic recurrent disease of the hepatobiliary system. Gallstones are the major cause of morbidity and mortality throughout the world. With atleast 10% of the adults have gallstones with a recent rise in the incidence due to change in the dietary factors. This study aims to evaluate the demographic factors, its various modes of presentation, treatment, outcome Method: This prospective study was conducted on 100 patients in General Surgery Ward, at Dr. D.Y. Patil Hospital and Research Centre, Pune for a period of 1 year who were diagnosed with cholelithiasis. Epidemiological aspects, Clinical profile, investigation, treatment and outcomes were analyzed. Result: The mean age of the patients was 36.82 years with male to female ratio 1:0.69. Pain abdomen was the most common symptom. Ultrasonography showed gallbladder stones in all patients and 31% of patients undergone open cholecystectomy and 65% underwent laparoscopic cholecystectomy.