Online ISSN: 2515-8260

Keywords : Clinical Study


Aetiological and Clinical Study of Atrial Fibrillation :An Observational Study in a Tertiary Care Hospital ,Telangana ,India

Dr.Rajeev Kumar Togiti, Dr.Raj Kumar Goud ,Dr.D.Kiran, Dr.Sharanya Vootla

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 4422-4432

Atrial fibrillation is the most common sustained arrhythmia seen in clinical practice. It is responsible for increased mortality from all cardiovascular causes and shortens average life span. Aims: To know the various clinical presentations in atrial fibrillation and to detect various aetiological factors of atrial fibrillation.Methodology: This Observational study was conducted on 50 cases of atrial fibrillation.Cases were examined in detail as per proforma with special reference to cardiovascular system.Investigations like urine examination, complete Blood picture, Erythrocytes Sedimentation rate, Blood urea, Serum creatinine, Blood sugar, Serum electrolytes and chest X-ray examination have been carried out. Special investigations like electrocardiogram, echocardiogram was also done. Whenever necessary blood for culture and sensitivity, CT-Brain in case of stroke. The electrocardiogram was studied for rate and ‘f’ wave pattern. The echocardiogram was studied to assess the valvular lesion, Mitral Valve Area (MVA) in mitral stenosis cases, and enlargement of chambers particularly the left atrium size.Results: Most of the chronic atrial fibrillation is associated with large left atrial size, 4-5cms (56%).Congestive cardiac failure (60%), angina (32%), embolic stroke (14%) are common complications.Incidence of congestive cardiac failure, angina are high in patients of chronic AF with fast ventricular rate.Incidence of embolic stroke is more in rheumatic AF.Incidence of embolic stroke is high in non-rheumatic AF with the presence of risk factors like age >65yrs, HTN, DM, CCF, LA size > 4.5 cm.Most of the cases of AF associated with MVA is less than 1 sq.cm. (Severe) in RHD.Conclusion: Atrial fibrillation due to rheumatic aetiology is more common in younger age group, while the other causes like hypertension, ischemic heart disease common in older age.Females are commonly affected than males.Rheumatic heart disease is commonest cause followed by ischemic heart disease, Hypertension.

Study of First Trimester Maternal Body Mass Index and Gestational Weight Gain and Their Association with Feto-Maternal Outcomes

Dr.Sravya Yatam; Dr. Sanjay Patil

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 5381-5391

Background: Pregnant women's body mass index (BMI) has increased recently, reflecting a general increase in the prevalence of obesity. High BMI before to conception and/or excessive gestational weight gain (GWG) have a negative impact on pregnancy outcomes, which raises the burden of chronic illnesses and jeopardies the health of both the mother and the unborn child.Aim:To study first trimester maternal Body Mass Index and gestational weight gain and their association with maternal and perinatal outcomes. Objective: To evaluate the effect of maternal BMI and gestational weight gain on fetomaternal outcome.Material & Methods:This was a prospective observational clinical study conducted in patients presenting to OPD of OBGY DEPARTMENT over a period of 18 months.The study was conducted among primigravida women visiting obstetrics OPD of our hospital during their first trimester pregnancy was comprise of my study population. Results:In present study, out of total 196 cases, first trimester BMI of 72 (36.7%) were found normal (<18.5-24.9 kg/m2) followed by 66 (33.7%) were found overweight (25.0-29.9 kg/m2). 35 (17.9%) were found in underweight (<18.5 kg/m2) whereas 23 (11.7%) were found Obese (>=30.0 kg/m2).out of total 46 cases in LWG, 42 (91.3%) cases were found Normal BW, 4 (8.7%) were found Low BW, none was found Macrosomia and 3 (6.5%) were required NICU admission. Out of total 92 cases in NWG, 88 (95.7%) were found Normal BW, 3 (3.3%) were found Low BW, 1 (1.1%) were found Macrosomia and 9 (9.8%) were required NICU admission. Out of total 58 cases in HWG, 53 (91.4%) cases were found Normal BW, 1 (1.7%) were found Low BW, 4 (6.9%) were found Macrosomia and 7 (12.1%) were required NICU admission.Conclusion: In clinical practice, this study recommend that women of childbearing age can be advised on the importance of maintaining an optimal BMI when planning to become pregnant.