European Journal of Molecular & Clinical Medicine

Background: Gastric carcinoma is the third most common cause of cancer related mortality worldwide. The present study is taken up to provide an overview of the spectrum of malignancies, age and sex incidence and risk factor such as tobacco usage, alcohol consumption, dietary intake and blood group analysis of gastric adenocarcinomas in South India.
Martial and Methods: The present study is a two year retrospective study that included all the cases received from   1^st August, 2018 to 31^st July 2020 in the department of pathology, Guntur Medical College and Government General Hospital, Guntur.
Results: A total of 49 cases were included in the study. The most common age group was sixth decade of life with male preponderance. Gastric outlet obstruction was the most common presenting symptom. Tubular type of gastric adenocarcinoma was the most common histopathological variant.
Conclusion: Regardless of growing understanding of the risk factors, phenotypic and genotypic alterations and diagnostic modalities, Gastric adenocarcinoma still linger to have poor prognosis due to limited treatment options.

Introduction: Swelling in the epigastrium is caused by those organs anatomically present in the region as well as by other organs in the other regions. This study was done with an interest to know the clinical presentation of the various cause of the epigastric swelling.
Methods: Fifty-two cases with a pathological swelling in the epigastrium, who were admitted to tertiary care center, were randomly selected those cases were studied during their stay in the hospital. In this study, the swelling from stomach and pancreas were included aged more than 12 years and the rest excluded. Relevant investigations were made and the diagnosis confirmed.
Results: There were 16 cases of pancreatic swellings and 11 cases of stomach swellings. Carcinoma stomach and pseudocyst each 21%, secondaries 17%, carcinoma pancreas 9.6%. Symptoms were Nausea (61.53%), pain (55.76%), vomiting (51.95%), weight loss (40.38%), fever (34.61%), anorexia (32.69%).
Conclusion: In this study, the most common swelling was the carcinoma stomach and pseudocyst of pancreas. Most common symptom was nausea, followed by pain, weight loss. The least common symptom was gastrointestinal bleeding