Online ISSN: 2515-8260

Keywords : HRCT chest

Sensitivity and specificity of RT PCR and HRCT Thorax for Confirmed Diagnosis ofCOVID-19

Siddharth Singh,Santosh Kumar Nayan,Sumeet Kumar,Abhay Kumar, Sweta Muni,Deepak Kumar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1437-1444

Introduction:TheCOVID-19pandemichasrepeatedlyhittheplanetwithawaveofinfection.Clinicians are attempting to defend public health care ethics. Asymptomatic COVID-19 casesgounrecorded,andthemajorityofthemisolatethemselves.Significantradiologicalabnormalities have been discovered in RT-PCR positive asymptomatic COVID-19 cases,accordingto studies.
Objective:Thegoalofthiscross-sectionalstudyistoevaluateasymptomaticRT-PCR-positivepatients'chest CT findingsin oneof India's COVID-designatedinstitutions in a tertiary care centre in Bihar.
Methods: In three months, we did HRCT chest of diverse (200 patient case study) proved andprobableinstances of COVID-19 infection. All patients are underwent HRCT chest by multislice (128 slice) Toshiba CT scan (Aquilion) or 16 slice Toshiba CT scan. The following CT parameters were used: collimation 5mm; slice thickness, 0.5- 2.5 mm; reconstruction interval, 2.5 mm; table speed 13.5 mm per rotation; 150 -250 mA effective current; tube potential 120kVp; and matrix size, 512 x 512. the patient was examined in supine position with both arms extended above the head. All CT chest were taken in caudocranial direction, covering entire chest from diaphragmatic dome up to lung apex, without intravenous contrast administration. The image finally send to PACS for reporting.
Results: Positive HRCT chest results were detected in 196 of 200 scanned individuals withclinical complaints and suspicion, indicating clinical-radiological association and an accuracyof 98 percent. Based on positive RT-PCR data, the sensitivity of chest CT in suggestingCOVID-19was98.6%(146/148patients).90percent(18/20)ofpatientswithnegativeRTPCRresultsandsignificantclinicalsuspicionhadpositivechestCTfindings.
Conclusion:InlaboratorynegativeRT-PCRcaseswithstrongclinicalsuspicionofCOVID-19infection,HRCTchestisparticularly sensitive and accurate in detecting up lung parenchymal abnormalities, as well asin all symptomatic patients whose RT-PCR was not done. In patients with a strong clinicalsuspicion,HRCTcanbeexceedinglysensitive,cost-effective,andtime-effective.HRCT outperformsRT-PCRintermsofprovidingimmediateresults,measuringdiseaseseverity,andprognosisprediction.
InallpatientswithclinicalsymptomsandsuspicionofCOVIDinfection,regardlessoflaboratoryRT-PCRstatus,werecommendHRCTchestforidentificationofearlyparenchymalabnormalities and determining diseaseseverity.

Evaluation of severity of Covid-19 inpatient by Computed tomography in tertiary centre of Bihar

Deepak kumar, Ashutosh Jha, Umakant Prasad, Sanjay Kumar Suman, Rashmi Rani Bharti, Amit Kumar, Dinesh, .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 111-117

Introduction- COVID -19 now become pandemic disease andChest computed tomography (CT) has very important role in diagnosis and characterizing the Covid patient severity by CT severity score.
Objectives:  The main purpose of this study was to evaluate the performance of MDCT in identifying & categorising the severity of COVID-19 inpatients.
Methods: This is retrospective cohort study and is performed on about 512 hospitalized COVID-19 patients in IGIMS from 15 April to July 2021. The CT severity score was assessed by two independent radiologists by involvement of percentage of area of each lobe of both lung parenchyma on HRCT lung. All admitted RT-PCR positive patient whose HRCT chest done in IGIMS were included in this study and OPD RT-PCR positive patient (COVID positive) & RT-PCR positive (COVID positive) patient with previous history of chronic lung disease, Tuberculosis, Lung mass, bronchiectasis etc were excluded in this study.
Results- In our study, Male (72.5%) are more affected in comparison to female (27.5%) and most of the patient are above the forth decade (69.5 %). Most patients are presented with severe CT severity score, i.e. > 15 CT severity score (about 41 percent) and about 20 percent & 22 percent present with mild & moderate CT severity score. Males are present with more CT severity than female.
Conclusion- Our studies show that older age group male patient (> 40 year) more affected in second peak of covid-19 and patient with chest involvement presented with severe CT severity score, so more mortality was noted , however this study is retrospective, needs prospective study for better correlation.

Role of HRCT chest in correlation of pulmonary tuberculosis with tuberculous spondylodiscitis

Dr. Ravi Soni, Dr. Suhail Khan, Dr. Bharat Jain, Dr. Shrinidhi Kulkarni, Dr. Monica Satyam, Dr. Kapil Vyas

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 897-903

Tuberculosis is a contagious bacterial infection which primarily affects the lung parenchyma
but it can affect any other part of the body. Mycobacterium tuberculosis complex is mainly
responsible for majority of cases in India and worldwide, but other species are also
responsible for causing tuberculosis among which includes M. bovis, M. africanum, M.
microti, M. Canetti. We retrospectively reviewed 40 patients of histologically or
microbiologically proven diagnosis of TB spondylitis from the time period of January 2020 to
October 2021 in the Radio-Diagnosis and Imaging Department of Pacific Medical College
and Hospital, Udaipur, Rajasthan, India. Findings such as cavitation, consolidation, tree in
bud opacities, miliary nodules are suggestive of pulmonary tuberculosis. Out of 5 patients
suffering from active pulmonary tuberculosis, cavitation was seen in 20% (1 patient) on chest
skiagram whereas 40% (2 patients) showed cavitation on HRCT chest. Consolidation was
seen in 60% (3 patients) on chest skiagram whereas it was seen in 80% (4 patients) on HRCT