European Journal of Molecular & Clinical Medicine

This study examined the neuroprotective effects of fractions- BMCT (Best Medium Chain Triglycerides) AMCT (All Medium Chain Triglycerides) and WCO (Whole Coconut Oil) of Cocos nucifera on the learning and memory in aluminium chloride induced brain dysfunction in rats. All Wistar rats of groups II to VI were received respective treatment doses (100/200 mg/kg) 30 minutes before oral administration of Aluminium chloride (100 mg/kg), daily for 42 days. On day 20, 21 and 42 following the start of aluminium chloride administration rats were subjected to evaluation of gross behavioral activity using Open field arena (OFA). Behavioral score recorded usingLine Crossing, Center Square Entries, Rearing and Grooming.

Background:Recent studies and literature regarding the use of “oil pulling” therapy especially using
virgin coconut oil have resulted in reduction of plaque-induced gingivitis. There are still a few evidences
in literature of studies regarding the properties of coconut oil in relation to the oral cavity.Hence, the
present study was conducted to assess the effect of coconut oil on plaque formation and plaque-induced
gingivitis.
Materials and method:45 Mild to moderate cases of plaque-induced gingivitis aged between 18-35 years
were enrolled in the study. Gingival Index and Modified Plaque Index were used for clinical assessment.
All the subjects after that were advised to take 10 ml of edible coconut oil and were instructed to follow
this procedure of oil pulling for 5 minutes after brushing the teeth, preferably in the morning on empty
stomach for 30 consecutive days. The parameters were recorded at baseline, 7th day, 15th day and 30th
day, for which the patients were recalled at these days for reevaluation of parameters used for assessment.
Results:The results of this study showed that out of 45 patients, 27(60%) were females and the remaining
18 (40%) were males. On statistical analysis, statistically significant difference was found Gingival Index
in the mean values Baseline and 7th day (p=0.000), Baseline and15th day (p=0.000), and Baseline and 30th
day (p=0.000).A statistically significant difference was found in the Plaque Index mean values Baseline
and 7th day (p=0.000), Baseline and 15th day (p=0.000), and Baseline and 30th day (p=0.000). A
statistically significant results in mean Plaque index was also observed between day 7 and 15 (p=0.000),
and day 15 and day 30. (p=0.000)
Conclusion: From day 7 and on a continuous decrease in the indexes was reported and they were
significantly reduced after 30 days of treatment. The results obtained from our study were significant,
relevant, and promising; however, to be more statistically significant outcome, more studies are required
to fully understand the mechanism of action of coconut oil.

The Regional Government of Sangihe Islands Regency, North Sulawesi, has designated Local Coconut Oil in Sangihe Language called "Lana Bango" as a Regional Superior Product. This study is a normative-legal research by using statute, case, and conceptual approaches. Data were analyzed with descriptive qualitative analysis with content analysis. In this study, the authors used the qualitative research method, which (in general) generates words rather than numbers as data for analysis. The approach used is observation and interpretation, which makes these phenomena observable. This paper provides information on the latest trend in research. The results show that the optimization of the Lana Bango production program must be carried out to support more profitable production prices for farmers. Local governments need to pay attention to all existing regulations so that they do not tend to violate regulations. Siding with the people should not be detrimental to other parties. Hence, the solution that can be carried out by the Sangihe Islands Regency Government when there is fluctuation in copra prices by optimizing other potentials of coconut plants. Last but not least, there are not contrary to regulations concerning the Prohibition of Monopolistic Practices and Unfair Business Competition.