Online ISSN: 2515-8260

Keywords : Dengue


MICROBIOLOGICAL PROFILE OF DENGUE CASES REPORTED AT GOVERNMENT GENERAL HOSPITAL, SIDDIPET

Dr.Taruni, Dr. S.L. Annapoorna

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 872-877

Introduction: Dengue fever, a mosquito-borne disease that occurs in tropical and subtropical
areas of the world, is considered to be a significant threat for the mankind in both developing
and developed countries.It causes a wide spectrum of illness from mild asymptomatic illness to
severe fatal dengue hemorrhagic fever/dengue shock syndrome. Its impact today is thirty times
>50 years ago. Global incidence of dengue has drastically upped in the last few years.
Materials and Methods: The study was carried out in the department of microbiology at
Government general hospital,siddipet fpr a period of one year , that is from January 2019 to
December 20219. Blood was collected from each patient suspected to be suffering from
dengue, at least 3 days after onset of fever. Serum was tested for the presence of dengue NS1
antigen and antihuman IgM antibodies using Panbio Dengue Early enzyme-linked
immunosorbent assay (ELISA) kit and National Institute of Virology. Results: A total of
samples
2251 were tested over a period of one years i.e. from January 2019 to December 2019. Out of
which 592 (26.29%) were sero-positive for dengue with symptoms of classical dengue fever.
IgM in 349(58.9%) NS1- 243 (41.04%). Conclusion: As vaccines or antiviral drugs are not
available for dengue viruses, the only effective way to prevent dengue is to control the
mosquito vector, Aedes aegypti and prevent its bite.

Analysis of the Dengue Infection, Occurrence and Hematological Profile of Dengue Patients in Dhaka City

Mohammad Zakerin Abedin; Md. Sifat Uz Zaman; Tasnim Ahmad; Md. Abdullah Al Maruf; Md Babul Aktar; Md. Fayez Ahmed; Md. Abu Sayeed Imran; Rubait Hasan; Pinki Akter; Md. Ekhlas Uddin

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 1572-1578

In the tropical and subtropical area, dengue virus is mostly found. To the determination of the occur-rence of dengue viral infection and hematological profile of dengue infected peoples in the Dhaka city. A sum of 255 samples of blood from both sex and different age groups were collected in this research. Dengue nonstructural protein 1 (NS1) and complete blood count (CBC) test were performed for the study. During this study period, total 255 samples were tested. Among these, 67samples were diagnosed as positive. Seroprevalence of dengue was 26.30%. Out of 67 positive dengue patients, 41 (61.2 %) were male and 26 (38.8 %) were female. Dengue infection was observed more in 21 to 30years age group followed by above 40years and 16 to 20years but observed less in of 1st day to 5years followed by 11 -15years, then 6 -10years and 31 - 40years. It was seen that the >40years of age group had the maximum unit of cases having low platelet count followed by 21-30years and it was also seen that 21-30years of age group had the maximum range of cases having low WBC count followed by above 40years of age group. In our research, we showed thrombocytopenia (100000 - 150,000/μl) with leucopenia (White Blood Cells, WBC <5000/μl) in 8(26.6%) cases and thrombocytopenia (100000-150,000/μl) without leucopenia in 9 (24.3%) cases but thrombocytopenia (<100000/μl) with leucopenia (White Blood Cells (WBC) < 5000/μl) in 5(16.7%) cases and thrombocytopenia (<100000/μl) without leucopenia in 6 (16.2%) cases. Among 67 positive cases, we found that (26.6%) had DF and (16.7%) had DHF according to WHO classification. For validating more reliability, this research needs further work.

Relationship Between Platelet, Hematocrit and Leukocyte with Dengue Severity in Bengkulu City, Indonesia

Dessy Triana; Annelin Kurniati; Gayatri Ghea Wirastari

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 10, Pages 2305-2311

Establishing the correct diagnosis of the clinical stage and the severity of dengue patients is very important to determine the prognosis. Examination of platelets, hematocrit and leukocytes for each clinical stage of dengue can help group and manage patients based on their clinical degree. This study aimed to determine the relationship between platelet, hematocrit and leukocyte examination results with the clinical degree of dengue based on WHO. This study used a cross-sectional study design with a sampling technique using consecutive sampling from July-November 2020 in 5 hospitals at Bengkulu City with total sample of 35 patients. The results found a strong relationship between hematocrit levels and the degree of severity of dengue (p = 0.001; r = 0.637). However, there was no significant relationship between the number of platelets (p = 0.826; r = -0.039) and leukocytes (p = 0.554; r = -0.103) with the severity of dengue. Laboratory tests are crucial to establish the clinical degree of dengue and disease’s prognosis.