European Journal of Molecular & Clinical Medicine

Background: Dentine hypersensitivity is a common complaint among dental patients.
Recently, a novel stabilized calcium sucrose phosphate dentifrice was introduced that offers a
desensitizing benefit. The primary aim of this study was to compare the in vivo efficacy of
this novel dentifrice with Calcium sodium phosphosilicate and a non-desensitizing dentifrice,
on dentin hypersensitivity in a four-week period.
Methods: Sixty volunteers with tooth sensitivity were recruited, and a double-blind,
randomized, parallel, controlled clinical trial was conducted in a hospital setting. Clinical
evaluation for dentin hypersensitivity by 0-10 VAS score was done using air blast, and cold
water methods. Following baseline measures, subjects were randomly divided into three
groups and treated as follows:
Group A: Dentifrice containing calcium sodium phosphosilicate (NovaMin).
Group B: Dentifrice containing Calcium sucrose phosphate.
Group C: Dentifrice containing no desensitizing ingredients. Clinical evaluations were
repeated after two and four weeks of product use.
Statistical analysis used: Mean VAS scores were compared among groups at different time
points (baseline, and 2 and 4 weeks) and among groups at each time point using one-way
analysis of variance.
Results: Compared to baseline, there was a clinically significant decrease in dentin
hypersensitivity in Groups A and B following four weeks use of the dentifrices containing
calcium sodium phosphosilicate and calcium sucrose phosphate, respectively. The Group A
dentifrice, however, was found to be significantly better in reducing the VAS score compared
to the Group B and Group C dentifrice at any time point for both measures of sensitivity.
Conclusion: The results suggest that the dentifrice containing 5% NovaMin provides rapid
and significantly more relief from dentin hypersensitivity in four weeks compared to a
dentifrice containing calcium sucrose phosphate or a non-desensitizing dentifrice.

Aim: The aim of this study was to assess prevalence of dentinal hypersensitivity and its association with diet and dietary habits among adults aged 18–30 years. Methods: A total of 389 subjects aged 18-30 years who reported to our institution with dentin sensitivity were considered. The questionnaire was given to subjects and were requested to complete the questionnaire and revert. Information about demographic data such as age, sex followed by details of their diet types; dietary habits and other associated habits were recorded. Results: Prevalence of dentinal hypersensitivity was found to be 44%. The subjects having dentinal hypersensitivity consumed more fizzy drinks with meals (OR=4.30), Aerated drinks (OR=3.04), consumption of fizzy drinks (OR=1.75) consumption of green leafy vegetable and junk foods along with sweet candies was not statistically associated with dentinal hypersensitivity (p<0.05). Twice brushing and use of fluoridated tooth paste did not yield a significant odds ratio. Conclusion: Consumption of fizzy rinks, aerated drinks has higher chances of developing dentinal hypersensitivity.