Introduction and Importance of the study-The neurological complications of leukaemia have common presenting symptoms but varying imaging abnormalities. Very few studies till date have been done in leukaemia patients in general regarding its CNS complications, direct as well as treatment related. Leukaemia has a very rapid course, therefore CNS complications are many times missed. Diagnosing CNS lesions in leukaemia is often difficult because there are no pathognomonic imaging features and histological verification is not possible in majority of the patients. CSF analysis has its own limitations and complications but is used for diagnosing because of lack of specific findings in MRI. As many CNS lesions in leukaemia are curable, early diagnosis is important for their proper management. The purpose of this study was to analyse the MRI imaging features of CNS complications of leukaemia and interpreting these MRI findings in view of clinical data to assess its value in early management. Results -70 patients were selected for the study MR abnormalities among the studied group were collected and classified according to age, gender, their time of development with respect to treatment and phase of treatment they were in. Various complications noted in our study were Posterior Reversible Encephalopathy Syndrome (PRES), infection, infiltration, infarction, Sino-venous thrombosis, haemorrhage, leukoencephalopathy, brain atrophy, spinal cord compressive myelopathy and cranial nerve involvement. Conclusion- To reach the correct diagnosis, the presenting signs, symptoms, and laboratory data must be considered along with the radiologic findings. MRI is known for its superior soft-tissue imaging; it was observed that MRI was helpful in the characterization of CNS lesions caused by the leukemic involvement of CNS structures and treatment-associated CNS complications and thus will lead to early management and prevention or minimizing the side effects of the disease.