Call for Papers
Submit your articles to the African Journal of Biomedical Research, active in Scopus Q3 and Clarivate Web of Science Zoological Records. Click here to submit your manuscript.
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COMPARISON OF EFFICACY AND SAFETY OF METFORMIN AND VILDAGLIPTIN VERSUS METFORMIN AND GLIMEPIRIDE IN PATIENTS OF TYPE – 2 DIABETES MELLITUS.
Volume 11 (2024) | Issue 5
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DETERMINING THE NEONATAL WEIGHT TREND AND THE FACTORS AFFECTING IT IN HEALTHY LATE PRETERM AND TERM NEONATES IN A TERTIARY CENTER.
Volume 11 (2024) | Issue 5
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TOOTH SIZE DISCREPANCY IN ORTHODONTIC PATIENTS AMONG DIFFERENT MALOCCLUSION GROUPS IN COIMBATORE (INDIAN)POPULATION- AN OBSERVATIONAL STUDY
Volume 11 (2024) | Issue 5
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EVALUATION OF CLEANING EFFICACY OF MANUAL K-FILE AND KEDO-S ROTARY FILE IN DECIDUOUS MOLAR: AN IN-VITRO STUDY
Volume 11 (2024) | Issue 5
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"A COMPARATIVE STUDY OF ULTRASOUND-GUIDED ERECTOR SPINAE BLOCK AND LOCAL INFILTRATION FOR LUMBAR SPINE FUSION SURGERIES”
Volume 11 (2024) | Issue 5
SYNTHESIS AND ANTIMICROBIAL SCREENING OF SOME 3-(4-SUBSTITUTED PHENYL)-2-PHENYL-4(3H)-QUINAZOLINONES
Main Article Content
Abstract
A new series of 3-(4-substituted phenyl)-2-phenyl-4-(3H)-quinazolinones 2(a-e) were synthesized by reacting 2-phenyl-4H-3-1-benzoxazin-4-one (1) with various primary amino compounds. The 2-phenyl-4H-3-1-benzoxazin-4-one (1) was prepared from anthranillic acid and benzoyl chloride. The structure of the title compounds was confirmed based on IR, 1H NMR, and Mass data. The compounds were screened for their antimicrobial activity and few of them were found to possess promising antimicrobial activity.
