Introduction: Chronic suppurative otitis media (CSOM) is worldwide in distribution. It is defined as ‘chronic or intermittent otorrhea through a persistent non intact tympanic membrane. Its incidence is higher in developing countries, like India. Various studies have shown both gram positive and gram negative organisms as causative agents of CSOM. Untreated CSOM leads to complications such as facial nerve paralysis, lateral sinus thrombosis, labyrinthitis, meningitis and brain abscess. Aim And Objectives: Aim of the study is to find out the aerobic bacteriological profile and their antibiotic sensitivity patterns in patients with chronic suppurative otitis media (CSOM) in our geographical area. Materials And Methods: This is a prospective cross sectional study done in 150 patients of CSOM presenting with active ear discharge. Sterile swabs were used to collect pus from discharging ear and sent for culture sensitivity. Results: Out of 150 samples tested,116 showed pure growth and 12 showed mixed growth and no growth seen in 22 samples. Among them, the most common organisms isolated were Pseudomonas aeruginosa and Staphylococcus aureus respectively. Pseudomonas aeruginosa was found to be more sensitive to Gentamicin followed by Meropenem. Staphylococcus aureus was found to be more sensitive to Linezolid followed by Doxycycline. Conclusion: Knowing the etiological agents causing CSOM and their antibiogram pattern is of paramount importance for a particular area. It aids in proper selection of topical/systemic antibiotics, along with keeping ear dry is the effective treatment modality of CSOM to prevent drug resistance, unwanted antibiotic administration and further complications.