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  2. Volume 7, Issue 7
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Online ISSN: 2515-8260

Volume7, Issue7

Comparative evaluation of efficacy of sub-gingivally delivered 2% indigenously prepared curcumin gel and 1% commercially available hexigel as an adjunct to scaling and root planing in chronic periodontitis patients : A split mouth randomized controlled clinical trial.

    Anupama Desai Harish Kumar Roquaiya Nishat Shivanand Aspalli Nagappa. G YAnand Kumar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5299-5312

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Abstract

Aim: To evaluate and compare the clinical efficacy of subgingivally delivered curcumin gel and hexigel as an adjunct to scaling and root planing in chronic periodontitis patients.
Materials and method:A total of 12 subjects of age 18-55years were randomly selected for the study from the Out Patient Department. A total of 36 sites with pocket depths ≥5 mm were chosen as a split mouth design at three different sites in the same patient. After scaling and root planning, in Group I -2% curcumin gel, in Group II- Chlorhexidinegel(Hexigel ) and in Group III-placebo gel (control)was placed sub-gingivally. Clinical parameters such as gingival index and plaque index were recorded at baseline, 7 days and 21 days. Pocket depth was checked at baseline, 21 and 45 days.
Results:All the groups showed statistically significant reduction in gingival, plaque indices and pocket depth. Group I(curcumin)as a local delivery agent showedcomparable results in terms of pocket depth reduction as group II (Hexigel).
Conclusion:Curcumin gel showed effective results and thus, can be used as an alternate to chlorhexidine gel in management of chronic periodontitis patient without any side effects
Keywords:
    Chlorhexidine Chronic periodontitis Curcumin Gingival index Plaque Index
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(2020). Comparative evaluation of efficacy of sub-gingivally delivered 2% indigenously prepared curcumin gel and 1% commercially available hexigel as an adjunct to scaling and root planing in chronic periodontitis patients : A split mouth randomized controlled clinical trial.. European Journal of Molecular & Clinical Medicine, 7(7), 5299-5312.
Anupama Desai; Harish Kumar; Roquaiya Nishat; Shivanand Aspalli; Nagappa. G; YAnand Kumar. "Comparative evaluation of efficacy of sub-gingivally delivered 2% indigenously prepared curcumin gel and 1% commercially available hexigel as an adjunct to scaling and root planing in chronic periodontitis patients : A split mouth randomized controlled clinical trial.". European Journal of Molecular & Clinical Medicine, 7, 7, 2020, 5299-5312.
(2020). 'Comparative evaluation of efficacy of sub-gingivally delivered 2% indigenously prepared curcumin gel and 1% commercially available hexigel as an adjunct to scaling and root planing in chronic periodontitis patients : A split mouth randomized controlled clinical trial.', European Journal of Molecular & Clinical Medicine, 7(7), pp. 5299-5312.
Comparative evaluation of efficacy of sub-gingivally delivered 2% indigenously prepared curcumin gel and 1% commercially available hexigel as an adjunct to scaling and root planing in chronic periodontitis patients : A split mouth randomized controlled clinical trial.. European Journal of Molecular & Clinical Medicine, 2020; 7(7): 5299-5312.
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