European Journal of Molecular & Clinical Medicine

Abstract

The most controversial issue in the study of the pathology of the temporomandibular system (TMJ) in childhood and adolescence is caused by etiopathogenetic aspects. Some researchers attribute the occurrence of this group of diseases to malocclusion [10,12, 20], while other authors focus more on age-related features of the growing organism, more precisely on a number of morphological and psychomotor processes that occur and end in the puberty and cause physiological abnormalities in a growing organism [7.19]. The third group of scientists approaches this issue with more modern views, that is, they put forward the role of metalloproteinases and markers of connective tissue for the formation of organs and tissues of the maxillofacial region (MFR).