European Journal of Molecular & Clinical Medicine

Abstract

Giant cell granuloma lesions are benign, non-odontogenic, moderately rare tumors of the oral cavity. They develop peripherally (within gingiva) or centrally (in bone)1 .The peripheral and central giant cell lesions (PGCL and CGCL) are a group of pathological entities with similar histopathological features and whose origin has not been fully elucidated. The former is reactive and the latter exhibits a nonneoplastic proliferative behavior.