Abstract

Background: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide and so are the disease-associated complications. The present study evaluated correlation of glycosylated hemoglobin (HbA1c) with microalbuminuria among diabetics.
Materials & Methods: 58 type II diabetics of both genders were enrolled. Blood pressure, smoking habit, family history of diabetes, renal disease and hypertension was recorded. Blood samples were analyzed for HbA1c, fasting blood glucose, postprandial blood glucose, serum urea and serum creatinine. Urine sample was analyzed for microalbuminuria.
Results: Out of 58 patients, males were 38 and females were 20. Duration of diabetes was 1-5 years in 27, 6-10 years in 20 and 10-15 years in 11 patients. Family history was positive in 23. Fasting blood glucose level was 182.4 mg/dl, PPBS level was 240.6 mg/dl and HbA1C was 9.15%. The difference was significant (P< 0.05). Microalbuminuria and glycemic control have shown a significant linear correlation with duration of diabetes (p<0.05). Also micro albuminuria has a significant negative correlation with increase in level of glycosylated haemoglobin.
Conclusion: The prevalence of microalbuminuria in diabetic patients was found to be high. Microalbuminuria has a significant negative correlation with increase in level of glycosylated haemoglobin.