Abstract

Objective: The current study aimed to compare the levels of zinc, alkaline phosphatase, and random blood sugar in people with leprosy to those in healthy controls from the Bundelkhand area. The second objective was to compare the correlation between study parameters in the leprosy group and the healthy control group. Material & methods:  The research was carried out in the Department of Biochemistry at Maharani Laxmi Bai Medical College (MLBMC) in Jhansi. In the healthy control group, forty human beings with normal glycemic status were age and gender matched. The leprosy patient group contained forty leprosy patients who were receiving treatment. Leprosy disease was diagnosed in accordance with the world health organization guidelines. Results: Age difference between the two groups was not statistically significant in the present investigation. Whereas, we found a statistically significant contrast between the two sets of data we analyzed, including RBS, ALP, and serum zinc levels. Leprosy patients showed a positive link between ALP and zinc, and a negative correlation between age and RBS; RBS and serum zinc. A positive connection between ALP and zinc was seen in the control group. We conclude that periodic monitoring of zinc concentrations in leprosy people may be prudent since zinc deficiency worsens insulin resistance and may lead to greater loss through urine.