European Journal of Molecular & Clinical Medicine

Abstract

Introduction:Diabetes mellitus is an important global public health problem. In addition to being a chronic disease, obesity is a key risk factor for Type 2 diabetes mellitus (T2DM) that leads to disability. This study aimed at investigating the effect of Body Mass Index on serum lipid profile in type II diabetic patients.
 
Material and Methods
This is a prospective study and observational study will be done in the Department of Physiology in collaboration     with the Department of Medicine, Index Medical College, Hospital & Research Centre, Indore.Inclusion Criteria:Only Diagnosed cases of male and female Type II Diabetes Mellitus cases aged 30-60 suffering from more than 2yrs. The diagnosis of diabetes is made on the basis of (Revised American Diabetic Association criteria). Fasting glucose >126mg/dl and 2hr postprandial plasma glucose >200mg/dl.
 
Results: The mean (± SD) of various motor nerve variables like latency, amplitude and nerve conduction velocity between control and cases. When compared these variables between controls and cases was statistically highly significant (p<0.001). Comparison of various motor nerve variables like latency, amplitude and nerve conduction velocity between control and cases are graphically shown.
 
Conclusion: A significant negative correlation between BMI and HDL-C was observed, while the correlation between BMI and LDL-C was observed to be insignificant. HDL-C was found significantly higher in patients with normal BMI. These results are important to indicate that there is modest impact of BMI on lipid profile. Therefore, assessment and management for altered blood lipids should not be based on a patient’s body weight or BMI.