European Journal of Molecular & Clinical Medicine

Abstract

Background:Diabetes mellitus (DM) referred as a group of metabolic disorders
characterized by high blood sugar levels over an extended period. The present study
was conducted to assess fasting and postprandial lipid profile in diabetic patient.
Materials & Methods:60type II diabetes patients of both genders were enrolled in group
I and 60 control in group II. Parameters such as HbA1c, FBS, PBS, total cholesterol
(TC), triglycerides (TG), high density lipoprotein – cholesterol (HDL-C), very-lowdensity
lipoprotein cholesterol (VLDL) and low-density lipoprotein cholesterol (LDL)
were assessed.
Results: Group I had 35 males and 25 females and group II had 28 males and 32
females. In group I and group II, mean PBS was 145.2 and 131.4, HbA1c was 9.4% and
4.5%, TG (mg/dl) was 184.2 and 150.3, TC (mg/dl) was 215.8 and 178.4, HDL- C (mg/dl)
was 44.2 and 58.2, VLDL (mg/dl) was 36.3 and 30.6 and LDL (mg/dl) was 170.4 and
85.2. The difference was significant (P< 0.05). The mean fasting and postprandial TG
value was 215.2 and 240.6, TC was 183.2 and 190.1, HDL- C was 44.2 and 37.3, VLDL
was 37.5 and 38.2 and LDL was 170.5 and 176.2 respectively. The difference was
significant (P< 0.05).
Conclusion: Postprandial lipid profile significantly increased when compared to fasting
lipid profile among type 2 DM patients.