Association of lichen planus with metabolic syndrome–acasecontrol study in a tertiary care center.
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 4, Pages 421-428
AbstractBackground: Lichen planus is an inflammatory papulosquamous dis- ease which affects skin and mucous membrane and cause metabolic derangements.
Methods: This is an hospital based case control study during a span of 2 year (Jan2018-Dec 2019) which includes 60 cases of lichen planus and 60 age and sex matched controls. Relevant clinical history and physical examination was done and collaborated with blood investigations. Diagnosis was made based on IDF criteria.
Results: No significant association can be established between lichen planus and metabolic syndrome ( p=0.278) Although prevalence of hypertension was higher in cases as compared to controls (36% vs. 26%, p=0.027) , TG levels (12% vs. 6%, p=0.030 and low HDLC levels (47% vs. 33%, p=0.039). No significant association was established between FBS and waist circumference with lichen planus.
Conclusions: Although no significant association can be established between lichen planus and metabolic syndrome but its components such as hypertension, TG and HDLC were found to be associated with LP as per the study. Therefore screening of these parameters in LP patients is necessary to avoid future complications in these patients.
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